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KMID : 0353019650020010021
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Korean Journal of Public Health
1965 Volume.2 No. 1 p.21 ~ p.29
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Experimental Studies on the Chronic Carbon-Monoxide Poisoning
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Abstract
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To observe changes in the hemogram, liver function, tissue oxygen consumption rate & body weight of rats those had been exposed to the 0.05%CO and the 0.1% CO atmosphere for 5 weeks, this study was undertaken following conclusions were observed.
1) Continuous increase of hemoglobin and hematocrit value was observed in the chronic 0.05% and the ch-ronic 0.1% carbon-monoxide exposure group and it was getting prominent at end if 4 weeks exposure up to final 5 weeks.
2) No remarkable changes of Mean Corpuscular Hemoglobin concentration were observed in the chronic 0.05% CO exposure group but slight increase in the chronic 0.1% CO exposure group could be observed.
2) Total plasma protein, albumin and Globulin decreased gradually as the exposure prolongs in both experim-ental group.
3) Icterus index showed no remarkable changes but slight increase in the chronic 0.1% CO exposure group was observed.
4) Tissue oxygen consumption rate increased in the end of 2 & 3 weeks exposure but returned to original value at the end of 4 & 5 weeks exposure.
5) The chronic CO exposure group showed continued body weight loss through the exposure and cessation of the growth in reference to the body weight could be seen.
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